Abstract

Objective: West Nile virus is one of the transfusion transmitted viral infections with worldwide distribution; it can cause severe disorders of the Central Nervous System. This research aimed to provide information about the sero prevalence of West Nile Virus among blood donors at Central Blood Bank, Khartoum State-Sudan. Methods: Ninety sera specimen were randomly collected from blood donors at Central Blood Bank . All collected sera specimen were tested for the presence anti-West Nile virus (IgM & IgG) antibodies by us ing semi-quantitative indirect ELISA. Results: Out of Ninety blood donor sera, 40 (44.4 %) were reactive for anti-WNV IgG antibody, whereas 2 (2.2%) were reactive for anti-WNV IgM antibody. Conclusion: In spite of higher percentage of Blood Donors at Central Blood Bank, Khartoum State-Sudan was exposed to West Nile virus, there were few recent cases. High care should be taken by health authorities for screening of blood donors, particularly when administered to immunocompromised patients.