Abstract

Objective: This study was carried out to assess identify new biochemical markers of azoospermia based on dosage of malonyldialdehyde and of total antioxidant capacity. Methods: The assay of MDA and TAC were carried out in the seminal plasma of 30 azoospermics and 30 normozoospermics. Normospermics served as the control group. Results: The average concentration of MDA in the seminal plasma of azoospermics was 16.86 ± 1,347μM and for normospermics was 17.88 ± 1.615 µM. They showed no significant difference with P > 0.05. The TAC of azoospermic was 2091 ± 88.93 µM and for normozoospermics the concentration was 1410 ± 196.7 µM. The concentration of the TAC, demonstrated a significant difference with P < 0.05. Conclusion: MDA in the seminal plasma presents no diagnostic value for azoospermia. However, the TAC is very high in azoospermics. Its evaluation may prove essential in the diagnosis of azoospermia.